Blinding in trials of interventional procedures is possible and worthwhile [version 2; referees: 3 approved]

Blinding in trials of interventional procedures is possible and worthwhile [version 2; referees: 3 approved]

Blog Article

In this paper, we use evidence from our earlier review of surgical randomised controlled trials with a placebo arm to show that blinding in trials of interventional procedures is feasible.We give examples of ingenious strategies that have been animed aniflex complete used to simulate the active procedure and to make the placebo control indistinguishable from the active treatment.We discuss why it is important to blind of patients, assessors, and caregivers and what types of bias that may occur in interventional trials.

Finally, we describe the benefits of blinding, from the obvious ones such as avoiding bias, as well as less evident benefits such click here as avoiding patient drop out in the control arm.